Systemic Diseases with Skin Manifestations for UPSC CMS: DM, SLE, Sarcoidosis and More

Diabetes Skin Manifestations#

Necrobiosis lipoidica (shin, yellow-brown plaques), Granuloma annulare, Diabetic dermopathy (brown spots on shins), Eruptive xanthomas (triglycerides >1000), Acanthosis nigricans (insulin resistance).

SLE Skin Signs#

Malar rash (butterfly, spares nasolabial fold), Discoid lesions (scarring), Photosensitivity, Oral ulcers, Alopecia, Vasculitic lesions.

Sarcoidosis#

Lupus pernio (violaceous nodules on nose/ears), Erythema nodosum (shins), Maculopapular rash. Non-caseating granulomas on biopsy.

Dermatomyositis#

Gottron papules (MCP/PIP joints), Heliotrope rash (eyelids), Shawl sign (shoulders), Mechanic hands.