Acute Coronary Syndrome
MONA-B: Morphine, Oxygen, Nitrates, Aspirin, Beta-blocker. STEMI: Primary PCI within 90 min (door-to-balloon). NSTEMI: Risk stratify (TIMI, GRACE), early invasive strategy if high risk.
Stroke
FAST screening. CT brain: exclude hemorrhage. IV tPA within 4.5 hours if ischemic. BP target <180/105 before thrombolysis.
Diabetic Ketoacidosis
1L NS/hr, Insulin 0.1 U/kg/hr, K+ replacement. Monitor glucose, electrolytes, venous blood gas. Bicarbonate only if pH < 6.9.
Acute Asthma
O2, SABA (Salbutamol nebulizers q20min), Ipratropium, Systemic steroids (Hydrocortisone). Magnesium sulfate if severe. Intubation if impending respiratory failure.
Sepsis
Sepsis-3 criteria: SOFA increase >= 2 + suspected infection. Surviving Sepsis 1-hour bundle: lactate, blood cultures, broad-spectrum antibiotics, 30mL/kg crystalloid for hypotension, vasopressors if MAP <65.
References & further reading
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Revision history
- 19 September 2026 — Initial publication
Frequently asked questions
What is MONA for ACS?
MONA = Morphine, Oxygen, Nitrates, Aspirin. Updated protocol: Aspirin 300mg chewable + P2Y12 inhibitor (Ticagrelor/Clopidogrel) + Anticoagulant (Heparin) + PCI if STEMI.
What is the stroke protocol?
FAST: Face droop, Arm weakness, Speech difficulty, Time (call emergency). For ischemic stroke within 4.5 hours: IV thrombolysis (tPA). For hemorrhagic: BP control, neurosurgical consultation.
What is the DKA management protocol?
Fluids (Normal saline 1L/hr), Insulin (0.1 U/kg/hr IV), Potassium replacement (if K < 3.3: hold insulin, give K). Monitor glucose hourly, electrolytes every 2-4 hours. Target: glucose <200, anion gap <12.
Related reading
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